03/10/2021
Sporting Braga 2 - 2 Boavista
Estoril 2 - 2 Gil Vicente
Benfica 0 - 1 Portimonense
Belenenses 0 - 2 Tondela
02/10/2021
Arouca 1 - 2 Sporting Lisbon
Porto 2 - 1 Paços Ferreira
Vizela 1 - 1 Santa Clara
01/10/2021
Famalicão 1 - 2 Vitoria Guimaraes
Marítimo 0 - 0 Moreirense
27/09/2021
Boavista 1 - 1 Estoril
Paços Ferreira 2 - 2 Belenenses
26/09/2021
Portimonense 0 - 0 Vizela
Santa Clara 1 - 1 Sporting Braga
25/09/2021
Tondela 3 - 2 Famalicão
Vitoria Guimaraes 1 - 3 Benfica
Moreirense 2 - 1 Arouca
24/09/2021
Gil Vicente 1 - 2 Porto
Sporting Lisbon 1 - 0 Marítimo
20/09/2021
Sporting Braga 3 - 1 Tondela
Benfica 3 - 1 Boavista